What a fun read!
Tom's granddad is peculiar and slightly eccentric but manages to splice body parts from different animals together and uses a formula to make them grow in size. After splicing parts of a salamander and a bat together to form a "dragon", some of the growth formula gets spilled on the floor where amoeba and ants come in contact with it. Tim's granddad is pressed to come up with a solution to shrink or exterminate the pests as they threaten to destroy the city.